NAICS 621320

Optometry Practices in South San Francisco, CA

The 1 ZIP codes assigned to South San Francisco contained 8 Optometry establishments in 2023.

Establishments (2023)
8
1 ZIP codes
10 or more employees
n/a
Practical financing floor
Share of county
17%
San Mateo County
City population
64,941
2025 estimate

Figures cover the ZIP codes the U.S. Postal Service assigns to South San Francisco (94080). ZIP areas are not municipal boundaries: they can extend beyond city limits and are shared between neighbouring places. This is a count of establishments in South San Francisco's ZIP codes, not a count of businesses inside its city limits.

Establishments by size

Employee-count distribution. For most buyers the businesses worth pursuing sit in the 5 to 49 range: large enough to have a manager and real systems, small enough to be owner-operated.

EmployeesEstablishmentsShareDistribution
1-4562.5%

How this market compares

South San Francisco against every other city in California on the same measure. City figures cover the ZIP codes assigned to the place rather than its municipal boundary, so they are compared as a share of the businesses in those same ZIP codes rather than per resident. Cities with fewer than 500 businesses in total are left unranked.

Densely served0.35% of local businesses, against 0.21% statewide

This industry takes up a far larger slice of the local business base than it does statewide. A crowded market: expect established competitors and price pressure, but also a deeper pool of businesses to buy.

Vs state share
+68%
Share of local businesses
Rank by count
#82
of 228 cities
Rank by share
#93
of 223 ranked
Since 2020
0%
Change in establishments

This compares how much of South San Francisco’s business base is optometry practices, against the California figure. Base: 2,283 establishments across all industries in the same ZIP codes, 2023. It does not measure revenue, profitability or whether a market is worth entering.

Business size mix

South San Francisco is more fragmented than California as a whole: a larger share of very small operators. Fragmented markets are where roll-ups are assembled, and where an owner nearing retirement has no obvious internal buyer.

Share of establishmentsSouth San FranciscoCaliforniaDifference
Under 5 employeesOwner-operated, often no management layer62.5%35.2%+27.3%
5 to 49 employeesThe range most individual buyers target0.0%17.9%-17.9%
10 or more employeesPractical floor for acquisition financing0.0%1.8%-1.8%

Nearest comparable markets

The closest places to South San Francisco that also have Optometry establishments on record. Useful for spotting a gap next door, or realising the market you are looking at is already served from the town over.

MarketEstablishmentsVs state share
San Bruno4+92%
Millbrae3+166%
Burlingame4-13%
San Mateo9-0%
Alameda9+127%

The wider San Mateo County market

Employment and payroll are reported at county level only, so the figures below describe the county South San Francisco sits in.

County establishments (2023)
47
San Mateo County
County employees
286
Mid-March employment
County annual payroll
$12M
All establishments
Full Optometry data for San Mateo County

What acquirers look at

Blends licensed professional services with high-margin retail optical. Retail revenue is transferable to a non-licensed owner in a way the clinical side is not.

Other industries in South San Francisco

Nearby cities

Sources

  1. U.S. Census Bureau, 2023 ZIP Code Business Patterns. Establishment counts and size distribution by ZIP code and NAICS, aggregated over the ZIP codes assigned to each city. Retrieved 2026-09-08.
  2. U.S. Census Bureau, 2023 County Business Patterns. Establishment counts, employment and annual payroll by NAICS. Retrieved 2026-09-08.
  3. U.S. Bureau of Labor Statistics, Quarterly Census of Employment and Wages (2026Q1). Quarterly establishment counts and employment for employers covered by unemployment insurance. Retrieved 2026-09-08.