NAICS 621610

Home Health & Home Care Services in South San Francisco, CA

The 1 ZIP codes assigned to South San Francisco contained 13 Home Health establishments in 2023, of which 7 employed 10 or more people.

Establishments (2023)
13
1 ZIP codes
10 or more employees
7
Practical financing floor
Share of county
15%
San Mateo County
City population
64,941
2025 estimate

Figures cover the ZIP codes the U.S. Postal Service assigns to South San Francisco (94080). ZIP areas are not municipal boundaries: they can extend beyond city limits and are shared between neighbouring places. This is a count of establishments in South San Francisco's ZIP codes, not a count of businesses inside its city limits.

Establishments by size

Employee-count distribution. For most buyers the businesses worth pursuing sit in the 5 to 49 range: large enough to have a manager and real systems, small enough to be owner-operated.

EmployeesEstablishmentsShareDistribution
5-9323.1%
10-19323.1%
20-49430.8%

How this market compares

South San Francisco against every other city in California on the same measure. City figures cover the ZIP codes assigned to the place rather than its municipal boundary, so they are compared as a share of the businesses in those same ZIP codes rather than per resident. Cities with fewer than 500 businesses in total are left unranked.

Above average0.57% of local businesses, against 0.49% statewide

A larger slice of the local business base than the statewide share. Usually a sign of genuine local demand rather than oversupply.

Vs state share
+16%
Share of local businesses
Rank by count
#90
of 220 cities
Rank by share
#81
of 211 ranked
Since 2020
0%
Change in establishments

This compares how much of South San Francisco’s business base is home health & home care services, against the California figure. Base: 2,283 establishments across all industries in the same ZIP codes, 2023. It does not measure revenue, profitability or whether a market is worth entering.

Business size mix

South San Francisco is more consolidated than California as a whole: fewer micro-operators and a larger share of businesses with real headcount. Fewer targets, but the ones that exist are more likely to be financeable.

Share of establishmentsSouth San FranciscoCaliforniaDifference
Under 5 employeesOwner-operated, often no management layer0.0%31.4%-31.4%
5 to 49 employeesThe range most individual buyers target76.9%28.3%+48.6%
10 or more employeesPractical floor for acquisition financing53.8%22.5%+31.3%

Nearest comparable markets

The closest places to South San Francisco that also have Home Health establishments on record. Useful for spotting a gap next door, or realising the market you are looking at is already served from the town over.

MarketEstablishmentsVs state share
San Bruno8+64%
Millbrae3+13%
Burlingame9-17%
Daly City10+32%
San Mateo23+9%

The wider San Mateo County market

Employment and payroll are reported at county level only, so the figures below describe the county South San Francisco sits in.

County establishments (2023)
85
San Mateo County
County employees
2,638
Mid-March employment
County annual payroll
$239M
All establishments
Full Home Health data for San Mateo County

What acquirers look at

Demographics guarantee demand growth. Licensure transfer and payor mix, private pay versus Medicaid, determine whether the business is actually financeable.

Other industries in South San Francisco

Nearby cities

Sources

  1. U.S. Census Bureau, 2023 ZIP Code Business Patterns. Establishment counts and size distribution by ZIP code and NAICS, aggregated over the ZIP codes assigned to each city. Retrieved 2026-09-08.
  2. U.S. Census Bureau, 2023 County Business Patterns. Establishment counts, employment and annual payroll by NAICS. Retrieved 2026-09-08.
  3. U.S. Bureau of Labor Statistics, Quarterly Census of Employment and Wages (2026Q1). Quarterly establishment counts and employment for employers covered by unemployment insurance. Retrieved 2026-09-08.