NAICS 446110

Independent Pharmacies in California

Establishments primarily engaged in retailing prescription and non-prescription drugs and medicines.

Establishments (2023)
4,247
Statewide, California
Employees
62,237
Mid-March employment
Annual payroll
$3.3B
All establishments
Avg. establishment size
14.7
Employees per establishment

What acquirers look at

PBM reimbursement pressure has compressed margins for a decade. Compounding, long-term-care contracts and clinical services are what make one viable.

Pharmacy by county

Ranked by establishment count, 2023 County Business Patterns. For the crowded-versus-underserved reading, see the saturation ranking, which ranks by establishments per resident instead.

#CountyEstablishmentsPer 10k residentsShare of state
1Los Angeles County1,4171.533.4%
2Orange County4661.511.0%
3San Diego County2910.96.9%
4Riverside County2441.05.7%
5San Bernardino County2201.05.2%
6Santa Clara County1510.83.6%
7Sacramento County1340.83.2%
8Alameda County1160.72.7%
9Ventura County1001.22.4%
10Fresno County950.92.2%
11Kern County951.02.2%
12San Francisco County941.12.2%
13Contra Costa County890.82.1%
14San Joaquin County540.71.3%
15San Mateo County540.71.3%
16Stanislaus County510.91.2%
17Tulare County481.01.1%
18Sonoma County380.80.9%
19Monterey County360.80.8%
20Placer County340.80.8%
21Santa Barbara County320.70.8%
22San Luis Obispo County311.10.7%
23Santa Cruz County301.20.7%
24Marin County291.10.7%
25Solano County240.50.6%

Counties in California

Sources

  1. U.S. Census Bureau, 2023 County Business Patterns. Establishment counts, employment and annual payroll by NAICS. Retrieved 2026-09-08.
  2. U.S. Bureau of Labor Statistics, Quarterly Census of Employment and Wages (2026Q1). Quarterly establishment counts and employment for employers covered by unemployment insurance. Retrieved 2026-09-08.