NAICS 446110

Independent Pharmacies in Los Angeles, CA

The 37 ZIP codes assigned to Los Angeles contained 271 Pharmacy establishments in 2023, of which 47 employed 10 or more people.

Establishments (2023)
271
37 ZIP codes
10 or more employees
47
Practical financing floor
Share of county
19%
Los Angeles County
City population
3,869,089
2025 estimate

Figures cover the ZIP codes the U.S. Postal Service assigns to Los Angeles (90001, 90004, 90006, 90011, 90012, 90013, 90015, 90016, 90019, 90020, 90022, 90023, and more). ZIP areas are not municipal boundaries: they can extend beyond city limits and are shared between neighbouring places. This is a count of establishments in Los Angeles' ZIP codes, not a count of businesses inside its city limits.

Establishments by size

Employee-count distribution. For most buyers the businesses worth pursuing sit in the 5 to 49 range: large enough to have a manager and real systems, small enough to be owner-operated.

EmployeesEstablishmentsShareDistribution
1-44516.6%
5-94918.1%
10-19176.3%
20-493011.1%

How this market compares

Los Angeles against every other city in California on the same measure. City figures cover the ZIP codes assigned to the place rather than its municipal boundary, so they are compared as a share of the businesses in those same ZIP codes rather than per resident. Cities with fewer than 500 businesses in total are left unranked.

Typical0.35% of local businesses, against 0.35% statewide

About the same slice of the local business base as the industry holds statewide.

Vs state share
-1%
Share of local businesses
Rank by count
#1
of 293 cities
Rank by share
#160
of 266 ranked
Since 2020
-8%
Change in establishments

This compares how much of Los Angeles’s business base is independent pharmacies, against the California figure. Base: 77,828 establishments across all industries in the same ZIP codes, 2023. It does not measure revenue, profitability or whether a market is worth entering.

Business size mix

Los Angeles is more fragmented than California as a whole: a larger share of very small operators. Fragmented markets are where roll-ups are assembled, and where an owner nearing retirement has no obvious internal buyer.

Share of establishmentsLos AngelesCaliforniaDifference
Under 5 employeesOwner-operated, often no management layer16.6%10.8%+5.9%
5 to 49 employeesThe range most individual buyers target35.4%38.9%-3.5%
10 or more employeesPractical floor for acquisition financing17.3%27.7%-10.4%

Nearest comparable markets

The closest places to Los Angeles that also have Pharmacy establishments on record. Useful for spotting a gap next door, or realising the market you are looking at is already served from the town over.

MarketEstablishmentsVs state share
Culver City9-13%
Beverly Hills33+36%
Santa Monica21-19%
West Hollywood5-49%
Inglewood9+27%

The wider Los Angeles County market

Employment and payroll are reported at county level only, so the figures below describe the county Los Angeles sits in.

County establishments (2023)
1,417
Los Angeles County
County employees
17,286
Mid-March employment
County annual payroll
$928M
All establishments
Full Pharmacy data for Los Angeles County

What acquirers look at

PBM reimbursement pressure has compressed margins for a decade. Compounding, long-term-care contracts and clinical services are what make one viable.

Other industries in Los Angeles

Nearby cities

Sources

  1. U.S. Census Bureau, 2023 ZIP Code Business Patterns. Establishment counts and size distribution by ZIP code and NAICS, aggregated over the ZIP codes assigned to each city. Retrieved 2026-09-08.
  2. U.S. Census Bureau, 2023 County Business Patterns. Establishment counts, employment and annual payroll by NAICS. Retrieved 2026-09-08.
  3. U.S. Bureau of Labor Statistics, Quarterly Census of Employment and Wages (2026Q1). Quarterly establishment counts and employment for employers covered by unemployment insurance. Retrieved 2026-09-08.