Orange County

Santa Ana, CA Business Index

Santa Ana is a city in Orange County with an estimated 315,586 residents as of 2025, up 1.4% since 2020. Santa Ana's business base is indexed below across 48 owner-operated industries.

Population (2025)
315,586
U.S. Census Bureau estimate
Change since 2020
+1.4%
2020–2025
Land area
27.4 sq mi
2023 Census Gazetteer
Density
11,528/sq mi
Residents per square mile

Population trend

Annual resident population estimates, U.S. Census Bureau Population Estimates Program.

YearPopulationYear over year
2020311,236n/a
2021311,060-0.06%
2022311,482+0.14%
2023312,247+0.25%
2024314,799+0.82%
2025315,586+0.25%

Santa Ana holds 10.0% of Orange County’s 3,149,507 residents.

Industries in Orange County

Santa Ana businesses compete in the Orange County market. Establishment counts, employment and payroll below are reported at county level by the U.S. Census Bureau.

Nearby cities

Other indexed places in Orange County and the surrounding area.

Data last refreshed from source on 2026-09-08.

Sources

  1. U.S. Census Bureau, Population Estimates Program (Vintage 2025). Subcounty resident population estimates. Retrieved 2026-09-08.
  2. U.S. Census Bureau, 2023 Gazetteer Files. Land area and internal point coordinates. Retrieved 2026-09-08.
  3. U.S. Census Bureau, ANSI/FIPS Place-to-County Relationship File Retrieved 2026-09-08.